Active ingredient: In each tablet; Contains 4 mg of onasetron (5 mg as hydrochloride dihydrate).

Excipients: Lactose (cow’s milk), corn starch, microcrystalline cellulose, methyl paraben (E218), propyl paraben (E216), magnesium stearate, purified talc, titanium dioxide, hydroxypropylmethyl cellulose, propylene glycol, erythrosine dyestuff, white beeswax and carnauba wax.

Before you start using this medicine, read this INSTRUCTIONS FOR USE carefully, because it contains important information for you.

Detailed information for this product is available in the patient information leaflet.

Instructions for proper use and dosage/frequency of administration

Take your medicine as your doctor tells you, the dose prescribed to you depends on the treatment you are taking. This leaflet generally tells you how much and how often you should take your medicine. If you are not sure, ask your doctor or pharmacist.

Vomiting after chemotherapy and radiotherapy: The recommended oral dose is 8 mg 1-2 hours before treatment, followed by 8 mg orally 12 hours later. To prevent delayed or prolonged vomiting after the first 24 hours, ZOFER treatment should be continued orally for up to 5 days after the treatment course. The recommended dose is 8 mg twice a day.

Chemotherapy with highly emetic properties: ZOFER can be administered orally, intravenously or intramuscularly. The recommended oral dose is 24 mg together with 12 mg oral dexamethasone sodium phosphate, 1-2 hours before treatment. To prevent delayed or prolonged vomiting after the first 24 hours, ZOFER treatment should be continued orally for up to 5 days following the treatment course. The recommended oral dose is 8 mg twice a day.

Postoperative nausea and vomiting: To prevent nausea and vomiting, the recommended oral dose is 16 mg as a single dose 1 hour before anesthesia. It is recommended to be administered as an injection in the treatment of postoperative nausea and vomiting.

Like all medicines, side effects may occur in people who are sensitive to the ingredients contained in ZOFER.

This medicine has not caused any problems in the majority of patients who use it.

If any of the following occur, stop using ZOFER and IMMEDIATELY inform your doctor or go to the emergency department of the nearest hospital.

These are all very serious side effects.

If you have one of these, it means you have a serious allergy to ZOFER. You may need emergency medical attention or hospitalization.

⚠️ Disclaimer: The information provided on this website is for informational purposes only and does not substitute professional medical advice. Always consult a healthcare provider before using any medication.