Excipients: Corn starch, crospovidone, talc, colloidal silicon dioxide (Aerosil 200), magnesium stearate, macrogol (PEG) 6000, quinoline yellow E 104, Eudragit E, titanium dioxide, glycerol triacetate, povidone (Colloidon 30).

Read this leaflet carefully before you start using this medicine, because it contains very important information for you.

(DL-Isoleucine α-ketoanolog), calcium salt

KETONEPHRO contains amino acids necessary for the body.

KETONEPHRO; It is in packages containing 100 or 300 bright yellow, film-coated tablets in blisters.

In chronic renal failure, prevention/treatment of damages that may occur due to insufficiency or deterioration of protein metabolism and the rate of progression of chronic renal failure

It is used in patients with predialysis (the period immediately before dialysis when there is an irreversible loss of 75% to 85% of kidney functions) with a low or preferably very low protein diet in which daily protein intake is restricted to 40 g or less in adults, in order to slow down the disease.

Instructions for proper use and dosage/frequency of administration

KETONEPHRO is given as long as the renal filtration rate (GFR: Glomerular filtration rate) is below 25 mL/minute. In the pre-dialysis period, the food adults consume at the same time should contain 40 g or less of protein per day. Protein intake of patients receiving dialysis treatment should comply with accepted norms.

For adults (70 kg/body weight); Take 4-8 tablets (1 tablet/5 kg/day) 3 times a day with meals.

Take the tablets with sufficient liquid.

Follow these instructions unless your doctor gives separate advice.

Like all medicines, side effects may occur in people who are sensitive to the ingredients contained in KETONEPHRO.

Very rarely, an increase in the calcium level in the blood may occur.

In this case, it is important to reduce vitamin D intake. If the increase in blood calcium level persists, reduce the dose of KETONEPHRO and other calcium sources.

If you experience any side effects not mentioned in this instruction manual, inform your doctor or pharmacist.

If you experience any side effects, whether listed in the Instructions for Use or not, talk to your doctor, pharmacist or nurse. Also, report the side effects you encounter to the Turkish Pharmacovigilance Center (TÜFAM) by clicking on the ‘Drug Side Effect Reporting’ icon on the website www.titck.gov.tr ​​or by calling the side effect reporting line at 0 800 314 00 08. By reporting any side effects that occur, you will contribute to obtaining more information about the safety of the medicine you are using.

⚠️ Disclaimer: The information provided on this website is for informational purposes only and does not substitute professional medical advice. Always consult a healthcare provider before using any medication.